the standard tire is a 140/80 18, FIM spec. Not sure where you are based, but here in southern africa we don't run the FIM spec tires and generally run MX type setups. (FIM has a limit on the length of the knobs to 18mm (i think) max, which is why they seem to go for the wider tread.
in terms of overall profile height, the 140/80 is 112mm (width is 140mm) which is basically 2mm larger than a 110/100 which is 110mm (width is 110mm), so there will be no noticeable gearing changes.
It has been a while since i have run FIM tires, but from others i believe that if you are not a spinner the FIM tires work well (which is why the likes of Chris Birch run that format) if you are aggressive and spin go for the MX config. i would guess the width will have an impact on the cornering of the bike, but not sure
What i can say is whatever you go for fit Tubliss ;-)
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2003 txt250 Pro
2013 Ossa 280i
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