Well, its a loaded question Dave.
The answer should be YES!
But it depends on where the idle screw is (height of the slide) and also the length of the straight section on the particular needle you are using.
Ideally at idle the straight section will be sitting in the nozzle/needle jet, restricting fuel pickup into the body. As you open the throttle and lift the slide the needle also rises in the nozzle and moves on to the tapers and increases fuel supply.
The pilot and airscrew are a totally independent circuit, however the combined effect still influences the idle mixture; therefore the diameter does affect this.
Times that it might not though, are usually when using a needle such as an N1EF which has a very short straight section before it leads into its taper. With this needle you can easily wind the idle screw in and lift the needle high enough to end up on the taper.
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