I can think of a reason to leave in the rimlock. If you get something puncturing the tire which stays in place - like a nail, etc. Then one tire ball will be punctured, at least in theory. With no rim-lock - As the wheel slips on the rim the tire balls will "roll" around inside the tire. Multiple tire balls could and probably would come in contact with the nail and be compromised.
Run with a rim lock and you get no wheel slippage in the rim and reduced chance of losing multiple tire balls...
jeff
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