Its true! I have a 2010 EC300R which uses the same 38mm ASII Carb, and have tried just about every combo of needle diameter, pilot, main, and clip position for the N1Ex, N3Ex, N3Cx, NEDx and NECx. The findings are well documented in the jetting section.
Thumperrider1 has implemented the NEDJ in his 2012 with good results, and I'm currently working with 2 others with 2012's in Australia to see what works for them. In my findings the stock needle has a really rich first taper, and a short straight section, which is what gives it the richness off the bottom (even if paired with a super lean pilot). The other needles work around this quite well. NEDx/NECx offer clean linear response, N3Ex/N3Cx have more of a mx transition in the mid range.
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